문헌 01warfarinICSR 검토우선순위 중간
Safety and efficacy of direct acting oral anticoagulants in the treatment of patients with morbid obesity with venous thromboembolism: A meta-analysis.
Direct acting oral anticoagulants (DOACs) are widely utilized in the management of venous thromboembolism. Numerous studies have demonstrated that their safety and efficacy surpass those of warfarin. Nevertheless, the evidence supporting their use in treating venous thrombosis among patients with m…
PMID42629703DOI10.1097/MD.0000000000050355연구 유형체계적 문헌고찰학술지Medicine
https://pubmed.ncbi.nlm.nih.gov/42629703/문헌 02apixabanICSR 검토우선순위 중간
Apixaban Versus Low-Molecular-Weight Heparin in Cancer-Associated Thrombosis: An Indication-Stratified Systematic Review and Meta-Analysis of Treatment and Postoperative Prophylaxis.
Apixaban is increasingly used as an alternative to low-molecular-weight heparin (LMWH) in patients with cancer, but evidence spans distinct clinical settings, including treatment of established cancer-associated thrombosis/venous thromboembolism (CAT/VTE) and postoperative thromboprophylaxis. We pe…
PMID42622790DOI10.1007/s10557-026-07908-0연구 유형체계적 문헌고찰, 리뷰학술지Cardiovascular drugs and therapy
https://pubmed.ncbi.nlm.nih.gov/42622790/문헌 03warfarinICSR 검토우선순위 중간
Venous thromboembolism prophylaxis in multiple myeloma patients receiving immunomodulatory therapy: a systematic review and meta-analysis.
Patients with multiple myeloma receiving immunomodulatory drugs have an increased risk of venous thromboembolism (VTE), but the comparative effectiveness and safety of available prophylactic strategies remain uncertain. A systematic review and meta-analysis of randomized and prospective studies was…
PMID42622759DOI10.1007/s11239-026-03380-7연구 유형리뷰학술지Journal of thrombosis and thrombolysis
https://pubmed.ncbi.nlm.nih.gov/42622759/문헌 04apixabanICSR 검토우선순위 중간
Staged Antithrombotic Reinitiation After STEMI Complicated by LV Thrombus and Intracerebral Hemorrhage.
Left ventricular thrombus after anterior ST-segment elevation myocardial infarction requires anticoagulation, and recent stenting requires dual antiplatelet therapy, but no guideline addresses antithrombotic sequencing when intracerebral hemorrhage complicates both. A 63-year-old woman developed an…
PMID42622585DOI10.1016/j.jaccas.2026.109886연구 유형증례보고학술지JACC. Case reports
https://pubmed.ncbi.nlm.nih.gov/42622585/문헌 05apixabanICSR 검토우선순위 중간
An Unusual Case of Appendicitis Entrapped Within a Spigelian Hernia.
Acute appendicitis within a Spigelian hernia is a rare clinical entity that may present with atypical symptoms, resulting in diagnostic delay and complex operative decision-making. Previously reported cases have most commonly presented with localized right lower quadrant pain, abdominal wall masses…
PMID42621588DOI10.7759/cureus.114778연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42621588/문헌 06dabigatran근거 검토우선순위 낮음
The use of direct oral anticoagulants in children with congenital and acquired heart disease.
Direct oral anticoagulants (DOACs), including the direct thrombin inhibitor, dabigatran, and factor Xa inhibitors (rivaroxaban, apixaban, and edoxaban), represent a significant advancement in pediatric anticoagulation therapy. Following U.S. FDA approvals for dabigatran and rivaroxaban in 2021 and…
PMID42630602DOI10.3389/fcvm.2026.1920897연구 유형리뷰학술지Frontiers in cardiovascular medicine
https://pubmed.ncbi.nlm.nih.gov/42630602/문헌 07dabigatran근거 검토우선순위 낮음
Safety in the Age of Artificial Intelligence: Evaluating Large Language Model Adherence to Antithrombotic Medication and Regional Anesthesia Guidelines.
The release of the 2025 American Society of Regional Anesthesia (ASRA) 5th edition guidelines for regional and neuraxial anesthesia procedures for patients receiving antithrombotic medications introduced complex, patient-specific hold times and resumption protocols. As clinicians increasingly utili…
PMID42614371DOI10.7759/cureus.114071연구 유형기타학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42614371/문헌 08apixabanICSR 검토우선순위 중간
Left Ventricular Thrombus Despite Prescribed Direct Oral Anticoagulant Therapy in Chronic Heart Failure With Reduced Ejection Fraction: A Case Report and Review of Risk Stratification.
Left ventricular thrombus (LVT) remains a clinically important complication associated with increased risks of systemic thromboembolism, ischemic stroke, and adverse cardiovascular outcomes. The optimal duration of anticoagulation treatment remains difficult to establish, and it should be individua…
PMID42633126DOI10.7759/cureus.113208연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42633126/문헌 09apixabanICSR 검토우선순위 중간
Apixaban vs Enoxaparin for Preventing Postoperative Thromboembolic events in Women Undergoing Surgery for Gynecologic Cancers: A Randomized Clinical Trial Study.
Venous thromboembolism (VTE), encompassing deep venous thrombosis and pulmonary embolism, presents a significant clinical risk for women undergoing surgical intervention for gynecologic malignancies. Enhanced prophylactic strategies are vital to mitigating these complications. This study evaluates…
PMID42610175DOI10.4103/ijnmr.ijnmr_205_24연구 유형기타학술지Iranian journal of nursing and midwifery research
https://pubmed.ncbi.nlm.nih.gov/42610175/문헌 10rivaroxabanICSR 검토우선순위 중간
Direct oral anticoagulants in cancer-associated venous thromboembolism: trial robustness and clinical trade-offs.
Although direct oral anticoagulants (DOACs) are often favored over low-molecular-weight heparin for cancer-associated thrombosis, the robustness of trial evidence supporting their use remains uncertain. We evaluated the efficacy, safety, and statistical robustness of DOACs vs dalteparin in patients…
PMID42620909DOI10.1016/j.rpth.2026.106844연구 유형기타학술지Research and practice in thrombosis and haemostasis
https://pubmed.ncbi.nlm.nih.gov/42620909/문헌 11rivaroxabanICSR 검토우선순위 중간
Alpha-1 antitrypsin deficiency associated with increased risk of venous thromboembolism: a nationwide cohort study in Denmark.
Mechanistic investigations suggest that alpha-1 antitrypsin may influence hemostatic processes; however, whether alpha-1 antitrypsin deficiency is associated with an elevated risk of venous thromboembolism is unclear. We tested whether alpha-1 antitrypsin deficiency is associated with venous thromb…
PMID42633228DOI10.1016/j.rpth.2026.106827연구 유형기타학술지Research and practice in thrombosis and haemostasis
https://pubmed.ncbi.nlm.nih.gov/42633228/문헌 12apixabanICSR 검토우선순위 중간
Intracavitary thrombus in the left ventricle and high-risk pulmonary embolism. A case report.
Massive pulmonary embolism (PE) is a life-threatening condition typically requiring systemic thrombolysis. The presence of a left ventricular (LV) thrombus represents a relative contraindication due to the high risk of systemic embolization, requiring individualized management. We present a 73-year…
PMID42615067DOI10.47487/apcyccv.v7i2.540.연구 유형증례보고학술지Archivos peruanos de cardiologia y cirugia cardiovascular
https://pubmed.ncbi.nlm.nih.gov/42615067/문헌 13rivaroxabanICSR 검토우선순위 중간
Reduced Versus Full Lead-In Apixaban or Rivaroxaban in Acute Venous Thromboembolism: A Systematic Review.
BackgroundDirect oral anticoagulants (DOACs) are recommended as first-line treatment for acute venous thromboembolism (VTE). The recommended regimen of apixaban and rivaroxaban requires a higher-intensity lead-in phase. However, clinicians may use reduced lead-in strategies due to concerns regardin…
PMID42610841DOI10.1177/10760296261452847연구 유형체계적 문헌고찰, 리뷰학술지Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
https://pubmed.ncbi.nlm.nih.gov/42610841/문헌 14apixabanICSR 검토우선순위 중간
Stroke and Recurrent Thrombosis of the Coronary Arteries Probably due to Patent Foramen Ovale and Antebrachial Vein Thrombosis in Patient with STEMI - Case Report.
A 74-year-old woman with a history of cryptogenic stroke in 2010 (during hospitalization at the neurological department, possible reasons of stroke were excluded at that time), with less than one year history of paroxysmal atrial fibrillation (AF), which was being treated with apixaban, and also ex…
PMID42609934DOI10.15388/Amed.2026.33.1.16연구 유형증례보고학술지Acta medica Lituanica
https://pubmed.ncbi.nlm.nih.gov/42609934/문헌 15warfarinICSR 검토우선순위 중간
Case Report: Direct Oral Anticoagulants Treatment Failure for Venous Thromboembolism in the Setting of Multiple Thrombophilic Conditions.
This case report describes the treatment failure of two direct oral anticoagulants (DOACs) in a patient with multiple thrombophilic conditions, including triple-positive antiphospholipid syndrome (APS) and heterozygous Factor V Leiden mutation. A 69-year-old male with a history of recurrent venous…
PMID42625323DOI10.1177/08971900261479657연구 유형기타학술지Journal of pharmacy practice
https://pubmed.ncbi.nlm.nih.gov/42625323/문헌 16rivaroxabanICSR 검토우선순위 중간
A Rare Presentation of Behçet's Disease: Coexistence of Intracardiac Thrombi, Coronary Artery Disease, and Pulmonary Thromboembolism.
Behçet's disease (BD) is a rare systemic vasculitis. While pulmonary involvement occurs, severe intracardiac manifestations are exceptional. We report a 44-year-old male presenting with dyspnea and hemoptysis. Multimodality imaging revealed bilateral pulmonary thromboembolism, severe three-vessel a…
PMID42605119DOI10.1002/ccd.70828연구 유형증례보고학술지Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
https://pubmed.ncbi.nlm.nih.gov/42605119/문헌 17rivaroxabanICSR 검토우선순위 중간
Interventional treatment of a bacterial embolus in the retrohepatic inferior vena cava secondary to invasive Klebsiella pneumoniae liver abscess syndrome: a case report and literature review.
Retrohepatic inferior vena cava (IVC) bacterial embolism secondary to invasive Klebsiella pneumoniae liver abscess syndrome (IKPLAS) is extremely rare, and no English literature has reported its interventional treatment to date. This study presents a detailed case of such interventional treatment,…
PMID42625683DOI10.3389/fcvm.2026.1923015연구 유형증례보고학술지Frontiers in cardiovascular medicine
https://pubmed.ncbi.nlm.nih.gov/42625683/문헌 18dabigatranICSR 검토우선순위 중간
Safety and effectiveness of dabigatran vs rivaroxaban in nonvalvular atrial fibrillation patients at nutritional risk.
Malnutrition is a prevalent comorbidity in nonvalvular atrial fibrillation (NVAF), yet comparative evidence on oral anticoagulants in this vulnerable population is scarce. We aimed to compare the safety and effectiveness of dabigatran with those of rivaroxaban in NVAF patients at nutritional risk.…
PMID42620299DOI10.1016/j.rpth.2026.106865연구 유형기타학술지Research and practice in thrombosis and haemostasis
https://pubmed.ncbi.nlm.nih.gov/42620299/문헌 19rivaroxabanICSR 검토우선순위 중간
Cutting-Edge Cardiology: Individualizing Antiplatelet Therapy for Optimal Acute Coronary Syndrome Outcomes.
Dual antiplatelet therapy (DAPT), consisting of aspirin and a P2Y12 inhibitor, is fundamental after percutaneous coronary intervention (PCI) in acute coronary syndromes (ACSs). Recent evidence supports moving from a uniform to an individualized approach, tailoring therapy duration and intensity to…
PMID42605337DOI10.7759/cureus.112849연구 유형리뷰학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42605337/문헌 20edoxabanICSR 검토우선순위 중간
Edoxaban plus aspirin de-escalation strategy versus continuous dual antithrombotic therapy in the perioperative period for patients with atrial fibrillation undergoing carotid artery stenting: a retrospective cohort study.
To compare the safety and efficacy of an edoxaban-based, time-limited dual antithrombotic therapy followed by a de-escalation strategy versus a continuous dual antithrombotic strategy in patients with atrial fibrillation (AF) undergoing carotid artery stenting (CAS). A total of 120 patients with CA…
PMID42631158DOI10.62347/KDDU9091연구 유형기타학술지American journal of translational research
https://pubmed.ncbi.nlm.nih.gov/42631158/문헌 21warfarinICSR 검토우선순위 중간
Massive aortic thrombus in a hypercoagulable patient with heparin induced thrombocytopenia: a case report.
Large ascending aortic thrombus can lead to devastating consequences and requires astute recognition and evaluation, systemic anticoagulation, and urgent surgical intervention. Perioperative and surgical management of a large ascending aortic thrombus is further complicated in patients who develop…
PMID42630987DOI10.1093/jscr/rjag455연구 유형증례보고학술지Journal of surgical case reports
https://pubmed.ncbi.nlm.nih.gov/42630987/문헌 22warfarinICSR 검토우선순위 중간
Real-World Hemocompatibility Outcomes With Aspirin Omission in a Novel Fully Magnetically Levitated Left Ventricular Assist Device.
Evidence from the fully magnetically levitated HeartMate 3 has suggested that aspirin omission may be safe and potentially beneficial. CH-VAD, a novel fully magnetically levitated ventricular assist device, has historically used standard anticoagulation protocols. This multicenter, retrospective st…
PMID42628015DOI10.1097/MAT.0000000000002816연구 유형기타학술지ASAIO journal (American Society for Artificial Internal Organs : 1992)
https://pubmed.ncbi.nlm.nih.gov/42628015/문헌 23warfarinICSR 검토우선순위 중간
Anticoagulation stewardship team oversight of enoxaparin-warfarin bridging delivered by Hospital in the Home: a pre- and post-implementation study.
Initiation or re-initiation of warfarin often requires enoxaparin bridging, a period associated with increased bleeding risk. Anticoagulation stewardship (ACS) teams may improve the safety of anticoagulant management; however, their impact on bridging delivered by Hospital in the Home (HITH) is unk…
PMID42605030DOI10.1111/imj.70590연구 유형기타학술지Internal medicine journal
https://pubmed.ncbi.nlm.nih.gov/42605030/문헌 24warfarinICSR 검토우선순위 중간
[Clinical characteristics, diagnosis, and treatment of 40 cases of venous thrombotic disease in children at a single center].
To investigate the clinical characteristics, diagnostic approach, multidisciplinary diagnosis and treatment model, and anticoagulation strategies of venous thrombotic disease in children, summarize diagnosis and treatment experience, and provide a reference for improving standardized management of…
PMID42608304DOI10.7499/j.issn.1008-8830.2511078연구 유형기타학술지Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
https://pubmed.ncbi.nlm.nih.gov/42608304/문헌 25warfarinICSR 검토우선순위 중간
Concomitant Aortic Valve Neocuspidization and Resection of a Cardiac Calcified Amorphous Tumor in a Hemodialysis Patient: A Case Report.
Cardiac calcified amorphous tumor (CAT) is an uncommon nonneoplastic intracardiac lesion associated with end-stage renal disease; mobile lesions carry an embolic risk and are generally resected. A 62-year-old man on maintenance hemodialysis was found to have a mobile verrucous mass 17 mm long on th…
PMID42605260DOI10.7759/cureus.114576연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42605260/문헌 26warfarinICSR 검토우선순위 중간
Peri-Procedural Healthcare Costs of Thromboembolic and Bleeding Events in Patients on Direct Oral Anticoagulants Undergoing High-Risk Endoscopy.
Patients on direct oral anticoagulants (DOACs) undergoing high-risk endoscopy face competing risks of bleeding and thromboembolism during peri-procedural anticoagulant interruption. We quantified peri-procedural adverse event (AE) rates and incremental healthcare costs. Retrospective cohort study u…
PMID42620337DOI10.64898/2026.07.31.26359377연구 유형기타학술지medRxiv : the preprint server for health sciences
https://pubmed.ncbi.nlm.nih.gov/42620337/문헌 27warfarinICSR 검토우선순위 중간
Direct Oral Anticoagulants Compared to Warfarin Early After Cardiac Surgery: A Pilot Randomized Controlled Trial.
The goal was to conduct a pilot randomized controlled trial (RCT) of direct oral anticoagulants (DOACs) early after cardiac surgery to determine the feasibility of a larger RCT. We conducted an open-label, 2-site, pilot RCT of adults undergoing cardiac surgery with an indication for anticoagulation…
PMID42610036DOI10.1016/j.cjco.2026.03.011연구 유형기타학술지CJC open
https://pubmed.ncbi.nlm.nih.gov/42610036/문헌 28warfarinICSR 검토우선순위 중간
Clinical Profile, Management Patterns, and In-Hospital Outcomes Among Patients Hospitalized With Atrial Fibrillation at a Tertiary Care Hospital: A Single-Center Retrospective Study.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide and is associated with substantial morbidity, mortality, recurrent hospitalization, and healthcare expenditure. This study aimed to evaluate the clinical characteristics, management patterns, and in-hospital outcomes…
PMID42621371DOI10.7759/cureus.112990연구 유형기타학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42621371/문헌 29warfarin근거 검토우선순위 낮음
Factors Associated With Time in Therapeutic Range Among Thai Patients with Non-valvular Atrial Fibrillation Taking Warfarin: Development of AHfHDP Score.
BackgroundIn Thai patients with non-valvular atrial fibrillation (NVAF), anticoagulation quality with warfarin remains suboptimal. Existing prediction tools for poor international normalized ratio (INR) control, such as the SAMe-TT 2 R 2 score, perform poorly in this population. Identifying populat…
PMID42615395DOI10.1177/10760296261480894연구 유형기타학술지Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
https://pubmed.ncbi.nlm.nih.gov/42615395/문헌 30tirzepatide근거 검토우선순위 낮음
Glucagon-like receptor-1 agonists and impotence: A meta-analysis.
Glucagon-like peptide receptors-1 agonists (GLP-1 agonists) have revolutionized the treatment of obesity and diabetes due to their potent effects on weight and glycemic control, and cardiorenal protection. However, emerging reports and post-marketing surveillance have raised concerns regarding erec…
PMID42626264DOI10.5662/wjm.119385연구 유형기타학술지World journal of methodology
https://pubmed.ncbi.nlm.nih.gov/42626264/문헌 31tirzepatide근거 검토우선순위 낮음
Comparative effects of semaglutide tirzepatide and retatrutide on renal fibrosis in UUO and aged mice.
Chronic kidney disease is a major health burden. Given the therapeutic potential of GLP-1 receptor agonists (semaglutide, tirzepatide, and retatrutide) in diabetic nephropathy, we evaluated their anti-fibrotic and anti-inflammatory effects in non-diabetic renal fibrosis using HK-2 cells and murine…
PMID42630988DOI10.1016/j.isci.2026.117174연구 유형기타학술지iScience
https://pubmed.ncbi.nlm.nih.gov/42630988/문헌 32tirzepatide근거 검토우선순위 낮음
Current and forthcoming pharmacotherapies for adolescent obesity: Evidence-based review.
The prevalence of adolescent obesity has increased substantially in recent decades. This disease affects more than 20% of young people. Obesity is associated with metabolic disorders and heart disease. Conservative treatments are not effective in severe obesity. Therefore, this minireview aims to c…
PMID42625929DOI10.5409/wjcp.118730연구 유형리뷰학술지World journal of clinical pediatrics
https://pubmed.ncbi.nlm.nih.gov/42625929/문헌 33tirzepatide근거 검토우선순위 낮음
Comment on Ostrominski et al. Comparative Effectiveness of Tirzepatide Versus Dulaglutide or Semaglutide on Major Cardiovascular Events in Type 2 Diabetes and Cardiovascular Disease: Insights From Two Target-Trial Emulations.
PubMed에 초록이 제공되지 않았습니다.
PMID42623541DOI10.2337/dc26-1171연구 유형기타학술지Diabetes care
https://pubmed.ncbi.nlm.nih.gov/42623541/문헌 34semaglutide근거 검토우선순위 낮음
Comment on Klein et al. Safety of Semaglutide After Dialysis Initiation: An Individual-Level Pooled Analysis.
PubMed에 초록이 제공되지 않았습니다.
PMID42623535DOI10.2337/dc26-1219연구 유형기타학술지Diabetes care
https://pubmed.ncbi.nlm.nih.gov/42623535/문헌 35semaglutide근거 검토우선순위 낮음
Response to Comment on Klein et al. Safety of Semaglutide After Dialysis Initiation: An Individual-Level Pooled Analysis.
PubMed에 초록이 제공되지 않았습니다.
PMID42623532DOI10.2337/dci26-0087연구 유형기타학술지Diabetes care
https://pubmed.ncbi.nlm.nih.gov/42623532/문헌 36semaglutide근거 검토우선순위 낮음
Hepatology: Emerging Paradigms in MASLD, Viral Hepatitis, Cholestatic Liver Disease, Portal Hypertension and Hepatocellular Carcinoma: Summary of the First Annual Paris International Liver Meeting 2026.
The Paris International Liver Meeting (January 19-21, 2026) brought together leading hepatology experts to discuss transformative advances in chronic liver disease management. The meeting highlighted pivotal developments reflecting the field's evolution from disease characterisation toward precisio…
PMID42613687DOI10.1111/liv.70806연구 유형리뷰학술지Liver international : official journal of the International Association for the Study of the Liver
https://pubmed.ncbi.nlm.nih.gov/42613687/문헌 37tirzepatide근거 검토우선순위 낮음
Responders Vs. Non-Responders or How to Predict the Response to GLP-1 or GLP-1/GIP Receptor Agonist Therapy.
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual GLP-1/GIP receptor agonists have transformed the pharmacological management of type 2 diabetes (T2D) and obesity, yet substantial interindividual variability in treatment response remains a defining clinical challenge. Narrative review.…
PMID42634284DOI10.1111/dom.71226연구 유형리뷰학술지Diabetes, obesity & metabolism
https://pubmed.ncbi.nlm.nih.gov/42634284/문헌 38semaglutide근거 검토우선순위 낮음
Targeting Overweight and Obesity Phenotypes for Secondary Prevention of Cardiovascular Disease: A Call to Action for the Middle East and Beyond.
Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause-effect relationship between OA…
PMID42634097DOI10.1111/obr.70204연구 유형리뷰학술지Obesity reviews : an official journal of the International Association for the Study of Obesity
https://pubmed.ncbi.nlm.nih.gov/42634097/문헌 39semaglutideICSR 검토우선순위 중간
Psychiatric and eye disorders associated with use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs).
Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) semaglutide, liraglutide, and dulaglutide are indicated for diabetes. Semaglutide and liraglutide were also approved for therapy of obesity or weight control. Apprehension has been expressed about the possible link between GLP-1 RAs and suicidal…
PMID42629417DOI10.1007/s00210-026-05813-9연구 유형기타학술지Naunyn-Schmiedeberg's archives of pharmacology
https://pubmed.ncbi.nlm.nih.gov/42629417/문헌 40tirzepatide근거 검토우선순위 낮음
A multi-functional oral small molecule targeting energy and lipid metabolism to treat obesity and related metabolic disorders.
Obesity and related metabolic disorders have surged globally, and are mechanistically interconnected through dysregulated energy and lipid metabolism pathways. Current incretin-based obesity treatments act to decrease food intake, but are associated with gastrointestinal side effects and muscle was…
PMID42627907DOI10.1126/sciadv.aed3119연구 유형기타학술지Science advances
https://pubmed.ncbi.nlm.nih.gov/42627907/문헌 41semaglutideICSR 검토우선순위 중간
GLP-1 receptor agonist therapy is associated with increased symptomatic remission in ulcerative colitis: a matched cohort study.
Ulcerative colitis (UC) remains associated with significant morbidity despite therapeutic advances. The impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on UC disease activity is not well defined. We performed a retrospective cohort study using electronic health records from a single…
PMID42627215DOI10.1093/ibd/izag167연구 유형기타학술지Inflammatory bowel diseases
https://pubmed.ncbi.nlm.nih.gov/42627215/문헌 42tirzepatide근거 검토우선순위 낮음
GLP-1 and GLP-1/GIP agonists in psoriasis: A real-world cohort study on healthcare resource usage.
PubMed에 초록이 제공되지 않았습니다.
PMID42627149DOI10.1111/jdv.70678연구 유형기타학술지Journal of the European Academy of Dermatology and Venereology : JEADV
https://pubmed.ncbi.nlm.nih.gov/42627149/문헌 43tirzepatideICSR 검토우선순위 중간
GLP-1 and dual GIP/GLP-1 receptor agonists' psychopharmacology and putative neuropsychiatric associated effects: a Bradford Hill-informed, systematic, evaluation.
This review evaluates evidence linking both GLP-1 and GIP/GLP-1RAs' exposure to a range of neuropsychiatric outcomes using the Bradford Hill criteria for causal inference. Glucagon-like peptide-1 (GLP-1) and the dual glucose-dependent insulinotropic polypeptide-GIP/GLP-1 receptor agonists (RAs) are…
PMID42624955DOI10.1007/s11920-026-01709-w연구 유형리뷰학술지Current psychiatry reports
https://pubmed.ncbi.nlm.nih.gov/42624955/문헌 44semaglutide근거 검토우선순위 낮음
Cognitive signs and symptoms in people with a psychiatric diagnosis on semaglutide: a retrospective cohort study of 13 007 patients in the USA.
Cognitive deficits across psychiatric disorders are common and difficult to treat. Semaglutide, a GLP-1 receptor agonist, shows potential cognitive benefits in diabetes and obesity, but effects in psychiatric populations remain unclear. To determine whether initiation of semaglutide is associated w…
PMID42624612DOI10.1136/bmjment-2026-302828연구 유형기타학술지BMJ mental health
https://pubmed.ncbi.nlm.nih.gov/42624612/문헌 45tirzepatide근거 검토우선순위 낮음
Trends in utilization of glucagon-like peptide‑1 receptor agonists, sodium-glucose cotransporter‑2 inhibitors, and metabolic bariatric surgery in U.S. Adults with diabetes and obesity.
To characterize trends in utilization of glucagon-like peptide‑1 receptor agonists (GLP‑1RAs), sodium-glucose cotransporter‑2 inhibitors (SGLT2is), and metabolic/bariatric surgery among US adults with type 2 diabetes (T2D) and obesity. We conducted a cohort study using electronic health record and…
PMID42624330DOI10.1016/j.diabres.2026.113504연구 유형기타학술지Diabetes research and clinical practice
https://pubmed.ncbi.nlm.nih.gov/42624330/문헌 46semaglutide근거 검토우선순위 낮음
A noninvasive 13 C-mannitol breath test to monitor semaglutide treatment-induced delayed oral-cecal transit in mice.
Glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide, are highly effective treatments for obesity and type 2 diabetes but are often associated with gastrointestinal side effects including delayed transit times through the gastrointestinal tract. We present a non-invasive breath…
PMID42623313DOI10.1152/ajpendo.00113.2026연구 유형기타학술지American journal of physiology. Endocrinology and metabolism
https://pubmed.ncbi.nlm.nih.gov/42623313/문헌 47semaglutide근거 검토우선순위 낮음
Semaglutide Alleviates LPS-Induced Cognitive Disorder via O-GlcNAcylation of AKT-mTOR Signaling Pathway Components.
Perioperative neurocognitive disorder (PND) manifests as neurocognitive alterations induced by anesthesia and surgical stress. High-risk factors, including advanced age, obesity, diabetes, and preoperative neurological dysfunction, accelerate PND progression, with neuroinflammation serving as a cor…
PMID42622904DOI10.1007/s12017-026-08945-6연구 유형동물시험학술지Neuromolecular medicine
https://pubmed.ncbi.nlm.nih.gov/42622904/문헌 48semaglutide근거 검토우선순위 낮음
Oral semaglutide vs DPP-4 inhibitors in reducing risk of cognitive impairment in elderly patients with HFpEF and obesity.
Heart failure with preserved ejection fraction (HFpEF), obesity, type 2 diabetes mellitus are common in elderly patients and are associated with an increased risk of cognitive impairment (CoI). In these patients, the protective metabolic and vascular effects of glucagon-like peptide-1 receptor agon…
PMID42622752DOI10.1007/s11739-026-04499-4연구 유형기타학술지Internal and emergency medicine
https://pubmed.ncbi.nlm.nih.gov/42622752/문헌 49semaglutide근거 검토우선순위 낮음
Oral semaglutide for obesity: clarifying comparative evidence and real-world applicability.
PubMed에 초록이 제공되지 않았습니다.
PMID42622205DOI10.1080/00325481.2026.2721720연구 유형기타학술지Postgraduate medicine
https://pubmed.ncbi.nlm.nih.gov/42622205/문헌 50tirzepatide근거 검토우선순위 낮음
Glucagon-like peptide-1 receptor agonists in idiopathic intracranial hypertension: A systematic review and meta-analysis.
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for type 2 diabetes and obesity, have emerged as promising candidates for idiopathic intracranial hypertension (IIH) due to their metabolic and neurophysiological effects. This systematic review and meta-analysis aims to sum…
PMID42619634DOI10.1111/head.70131연구 유형리뷰학술지Headache
https://pubmed.ncbi.nlm.nih.gov/42619634/문헌 51semaglutide근거 검토우선순위 낮음
Native Mass Spectrometry of Soluble Proteins with Sodium Chloride Enabled by a Dendritic Detergent.
Salts are essential for maintaining native protein structure and biomolecular interactions. Native mass spectrometry often yields uninterpretable spectra due to salt adduction and signal suppression. Existing workarounds require buffer exchange or extensive cleanup, which can disrupt weak noncovale…
PMID42631177DOI10.1021/acsmeasuresciau.6c00038연구 유형기타학술지ACS measurement science au
https://pubmed.ncbi.nlm.nih.gov/42631177/문헌 52semaglutide근거 검토우선순위 낮음
Response to "Semaglutide in Diabetic Periodontitis-Induced Osteoblast Ferroptosis: Pharmacological and Methodological Insights" [Response to Letter].
PubMed에 초록이 제공되지 않았습니다.
PMID42633295DOI10.2147/DDDT.S642305연구 유형기타학술지Drug design, development and therapy
https://pubmed.ncbi.nlm.nih.gov/42633295/문헌 53semaglutide근거 검토우선순위 낮음
Daily briefing: Narcolepsy drug could kick off an Ozempic-style moment for the brain.
PubMed에 초록이 제공되지 않았습니다.
PMID42613446DOI10.1038/d41586-026-02589-z연구 유형기타학술지Nature
https://pubmed.ncbi.nlm.nih.gov/42613446/문헌 54semaglutide근거 검토우선순위 낮음
Doctor who prescribed Ozempic and Wegovy to her partner has suspension extended.
PubMed에 초록이 제공되지 않았습니다.
PMID42608058DOI10.1136/bmj-2026-100590연구 유형기타학술지BMJ (Clinical research ed.)
https://pubmed.ncbi.nlm.nih.gov/42608058/문헌 55semaglutide근거 검토우선순위 낮음
Compounding stigma: An experimental study comparing perceptions of an individual using Ozempic, bariatric surgery, or behavior modification.
Weight loss is a billion-dollar industry; methods of weight loss influence weight stigma and person perception. Prior research suggests individuals undergoing bariatric surgery face compounding prejudice from both their physical condition and the surgery itself. Bariatric surgery is often viewed as…
PMID42612445DOI10.1016/j.socscimed.2026.119710연구 유형기타학술지Social science & medicine (1982)
https://pubmed.ncbi.nlm.nih.gov/42612445/문헌 56semaglutide근거 검토우선순위 낮음
Exploring Perspectives on Ozempic: A Netnographic Qualitative Evaluation of the Pro-Eating Disorder Community on X (Formerly Twitter).
Eating disorders (EDs) are complex conditions with medical and psychosocial implications. Social media (SM) exposure has been associated with increased body image concerns and maladaptive eating behaviors. Pro-eating disorder (pro-ED) communities exist across SM platforms and often perpetuate ED-re…
PMID42604953DOI10.1002/eat.70190연구 유형기타학술지The International journal of eating disorders
https://pubmed.ncbi.nlm.nih.gov/42604953/문헌 57tirzepatide근거 검토우선순위 낮음
Practical considerations for the use of incretin mimetics in patients with neuroendocrine neoplasms: An expert consensus statement.
Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RA) and dual incretin agonists, are increasingly used for the management of diabetes, obesity, and cardiometabolic disease. Although their systemic benefits are well established, uncertainty remains regarding their…
PMID42606162DOI10.1002/cncr.70586연구 유형리뷰학술지Cancer
https://pubmed.ncbi.nlm.nih.gov/42606162/문헌 58semaglutide근거 검토우선순위 낮음
Serum GDF3 is Associated with Visceral Obesity, Insulin Resistance, and Inflammation in Non-Diabetic Adults: A Cross-Sectional Study with an Interventional Component.
Growth differentiation factor 3 (GDF3), a TGFβ superfamily cytokine, has been linked to visceral adipose proliferation and adiposity in animal studies. However, the relationship between circulating GDF3 levels and visceral adiposity in humans remains unclear. This study aimed to assess the potentia…
PMID42610056DOI10.2147/DMSO.S609998연구 유형기타학술지Diabetes, metabolic syndrome and obesity : targets and therapy
https://pubmed.ncbi.nlm.nih.gov/42610056/문헌 59tirzepatide근거 검토우선순위 낮음
Comparative Efficacy of Semaglutide and Tirzepatide in Chinese Adults with Obesity without Diabetes: A Real-World Observational Study.
To conduct a direct comparison of the effects of Semaglutide and Tirzepatide among adults with obesity but without diabetes. From January 2024 to February 2026, a total of 183 Chinese adults were enrolled from the obesity clinic at our hospital in a single-center, retrospective observational cohort…
PMID42610030DOI10.2147/DMSO.S607678연구 유형기타학술지Diabetes, metabolic syndrome and obesity : targets and therapy
https://pubmed.ncbi.nlm.nih.gov/42610030/문헌 60semaglutide근거 검토우선순위 낮음
Quality and reliability of semaglutide-related health information on Chinese short-video platforms: a cross-sectional study of Bilibili and TikTok.
Semaglutide, a glucagon-like peptide-1 receptor agonist originally developed for glycemic control, has recently gained widespread attention for its weight-loss effects. With the rapid rise of short-video platforms, these media have become important channels for disseminating health information. How…
PMID42620396DOI10.3389/fpubh.2026.1826485연구 유형기타학술지Frontiers in public health
https://pubmed.ncbi.nlm.nih.gov/42620396/문헌 61semaglutideICSR 검토우선순위 중간
Not Just for Diabetes: The Next Frontier for GLP-1 Agonists.
A commonly used GLP-1 agonist, semaglutide, reduces the risk of adverse cardiovascular outcomes in non-diabetic individuals with obesity and pre-existing cardiovascular disease.
PMID42624784DOI10.3122/jabfm.2025.250473R1연구 유형기타학술지Journal of the American Board of Family Medicine : JABFM
https://pubmed.ncbi.nlm.nih.gov/42624784/문헌 62semaglutide근거 검토우선순위 낮음
Semaglutide-Induced Nonarteritic Anterior Ischemic Optic Neuropathy: A Systematic Review and Meta-Analysis.
Despite the recent reports of the potential association between semaglutide and nonarteritic anterior ischemic optic neuropathy (NAION), available evidence remains inconclusive. We aimed to evaluate the relative effect (RE) of NAION in individuals treated with semaglutide compared to the control gr…
PMID42612051DOI10.1002/jcph.70248연구 유형체계적 문헌고찰, 리뷰학술지Journal of clinical pharmacology
https://pubmed.ncbi.nlm.nih.gov/42612051/문헌 63semaglutideICSR 검토우선순위 중간
The GLP-1-Mitochondria Axis in Metabolic Aging.
Metabolic aging underlies a cluster of chronic conditions-type 2 diabetes, cardiovascular disease, sarcopenia, and neurodegeneration-that account for a substantial share of global morbidity and mortality. A common feature is progressive mitochondrial dysfunction: impaired bioenergetics, disrupted q…
PMID42608657DOI10.1111/acel.70676연구 유형리뷰학술지Aging cell
https://pubmed.ncbi.nlm.nih.gov/42608657/문헌 64semaglutideICSR 검토우선순위 중간
Severe Gastrointestinal Intolerance After Resuming Maintenance-Dose Semaglutide Following Ramadan-Related Treatment Interruption: A Case Report.
Glucagon-like peptide-1 (GLP-1) receptor agonists are widely used in the treatment of obesity and diabetes mellitus because of their efficacy in weight reduction, glycemic control, and overall metabolic benefits. Gastrointestinal adverse events are among the most frequently reported side effects as…
PMID42622003DOI10.7759/cureus.113026연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42622003/문헌 65semaglutideICSR 검토우선순위 중간
Semaglutide for Refractory Reactive Hypoglycaemia: A Case Report.
Reactive hypoglycaemia is characterised by symptomatic hypoglycaemia occurring several hours after food intake and can significantly impair quality of life. Management is often challenging, particularly in patients who fail dietary modification or cannot tolerate conventional pharmacological therap…
PMID42605357DOI10.7759/cureus.112861연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42605357/문헌 66tirzepatideICSR 검토우선순위 중간
GLP-1 Receptor Agonists and Alopecia: A Systematic Review and Meta-Analysis of Incidence, Risk, Subtypes, and Mechanisms.
GLP-1 receptor agonists (GLP-1 RAs) are among the fastest-growing pharmacological classes globally. Alopecia has emerged as a clinically relevant adverse effect signal, yet pooled quantitative estimates of risk by subtype and agent are lacking. The objective of this study was to estimate the pooled…
PMID42621629DOI10.1159/000553070연구 유형리뷰학술지Skin appendage disorders
https://pubmed.ncbi.nlm.nih.gov/42621629/문헌 67tirzepatide근거 검토우선순위 낮음
Attitudes Toward Injectable GLP-1 Drugs for Obesity Treatment: A Qualitative Interview Study With Healthcare Professionals.
Injectable GLP-1 drugs such as semaglutide (Wegovy) and tirzepatide (Mounjaro, a dual GLP-1 and GIP receptor agonist) can help individuals living with obesity to lose weight. UK guidelines currently recommend semaglutide and other injectable GLP-1 drugs are prescribed in specialist (Tier 3) multidi…
PMID42630863DOI10.1002/osp4.70130연구 유형기타학술지Obesity science & practice
https://pubmed.ncbi.nlm.nih.gov/42630863/문헌 68semaglutide근거 검토우선순위 낮음
Beyond Small Molecules: Applying Fragment Molecular Orbital Sygnature Platform (FMO-SP) to Emerging Modalities.
Drug discovery is rapidly expanding beyond traditional small molecules to encompass new therapeutic modalities capable of addressing previously "undruggable" targets. Between 2015 and mid-2025, FDA approvals increasingly included biologics and emerging therapeutic modalities such as antibody-drug c…
PMID42604899DOI10.1007/978-1-0716-5420-0_6연구 유형기타학술지Methods in molecular biology (Clifton, N.J.)
https://pubmed.ncbi.nlm.nih.gov/42604899/문헌 69tirzepatide근거 검토우선순위 낮음
Pancreatic-liver crosstalk, novel molecular mediators, and 2025 therapeutic breakthroughs.
Obesity, a global public health crisis driven by dysregulated systemic energy homeostasis, is increasingly recognized as a disorder of interorgan communication, with the pancreas and liver serving as central interconnected metabolic hubs. Their bidirectional crosstalk, mediated through neural and h…
PMID42626202DOI10.5662/wjm.v16.i3.118728연구 유형리뷰학술지World journal of methodology
https://pubmed.ncbi.nlm.nih.gov/42626202/문헌 70tirzepatide근거 검토우선순위 낮음
Weight loss outcomes with tirzepatide in women with and without self-reported polycystic ovary syndrome.
Weight management is key to managing polycystic ovary syndrome (PCOS) and overweight/obesity but is challenging for many. Evidence regarding tirzepatide's efficacy in women with polycystic ovary syndrome is limited. To quantify the effectiveness of tirzepatide for weight loss in women with (self-re…
PMID42634795DOI10.1210/jendso/bvag177연구 유형기타학술지Journal of the Endocrine Society
https://pubmed.ncbi.nlm.nih.gov/42634795/문헌 71tirzepatideICSR 검토우선순위 중간
Increasing skeletal muscle mass and strength during incretin-based weight loss.
Incretin-based therapies produce robust weight loss in obesity and type 2 diabetes mellitus (T2DM), but some weight lost is lean body mass (LBM), raising concern about sarcopenia and functional decline. Men with obesity or type 2 diabetes (T2DM) and testosterone deficiency may lose skeletal muscle…
PMID42620560DOI10.1016/j.obpill.2026.100317연구 유형기타학술지Obesity pillars
https://pubmed.ncbi.nlm.nih.gov/42620560/문헌 72tirzepatide근거 검토우선순위 낮음
Weekly Journal Scan: SURMOUNT and MAINTAIN the summit: tirzepatide after successful bodyweight loss.
PubMed에 초록이 제공되지 않았습니다.
PMID42619286DOI10.1093/eurheartj/ehag621연구 유형기타학술지European heart journal
https://pubmed.ncbi.nlm.nih.gov/42619286/문헌 73tirzepatide근거 검토우선순위 낮음
Clinical efficacy of switching to tirzepatide in patients with type 2 diabetes and a high risk of metabolic dysfunction-associated steatotic liver disease undergoing GLP-1 receptor agonist therapy: Insights from the Hokkaido-TZP study.
To evaluate the clinical efficacy of switching from glucagon-like peptide-1 receptor agonists (GLP-1RAs) to tirzepatide in terms of metabolic and hepatic indices in patients with T2D at high risk of metabolic dysfunction-associated steatotic liver disease (MASLD). This multicenter, retrospective st…
PMID42618422DOI10.1016/j.jdiacomp.2026.109391연구 유형기타학술지Journal of diabetes and its complications
https://pubmed.ncbi.nlm.nih.gov/42618422/문헌 74tirzepatide근거 검토우선순위 낮음
Venous Congestion in Metabolic Heart Disease: Potential Indirect Role of Dual Incretin Agonists.
Venous congestion is responsible for symptoms, organ dysfunction, and negative outcomes in heart failure. In obesity-related Heart Failure (HF) with preserved ejection fraction (HFpEF), metabolic dysfunction, inflammation, endothelial damage, and sodium retention might exacerbate venous congestion.…
PMID42634315DOI10.2174/011871529X502187260803101832연구 유형기타학술지Cardiovascular & hematological disorders drug targets
https://pubmed.ncbi.nlm.nih.gov/42634315/문헌 75tirzepatideICSR 검토우선순위 중간
The Neuroprotective Potentials of Dual GIP/GLP1-RA (Tirzepatide): From Preclinical Experiments to Clinical Trials: A Scoping Review.
Tirzepatide (TZP), the first approved dual glucagon-like peptide 1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) agonist, has shown neuroprotective effects in preclinical models and early observational studies. This review maps and appraises current preclinical and clinical evidence on…
PMID42608956DOI10.1002/brb3.71702연구 유형리뷰학술지Brain and behavior
https://pubmed.ncbi.nlm.nih.gov/42608956/문헌 76tirzepatideICSR 검토우선순위 중간
Severe Dumping and Persistent Obesity in a Post-Roux-en-Y Gastric Bypass Patient With a Non-discernible Gastric Pouch and Symptomatic Improvement on Tirzepatide: A Case Report.
Rapid transit of ingested nutrients into the small bowel following gastric or esophageal surgery can trigger dumping syndrome, a recognized postoperative complication seen with particular frequency after Roux-en-Y gastric bypass (RYGB). Under normal operative conditions, RYGB constructs a proximal…
PMID42634712DOI10.7759/cureus.113316연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42634712/문헌 77tirzepatideICSR 검토우선순위 중간
Sex-based differences in clinical outcomes among patients with obesity and heart failure with preserved ejection fraction treated with tirzepatide.
BackgroundSex-related differences are well recognized in heart failure with preserved ejection fraction (HFpEF), but real-world data describing clinical outcomes by sex among patients with obesity and HFpEF treated with tirzepatide remain limited.ObjectivesTo compare observed hospitalization, cardi…
PMID42605954DOI10.1177/17539447261478928연구 유형기타학술지Therapeutic advances in cardiovascular disease
https://pubmed.ncbi.nlm.nih.gov/42605954/문헌 78tirzepatideICSR 검토우선순위 중간
Efficacy and safety of different once-weekly glucagon-like peptide-1 receptor agonists-A systematic review and Bayesian network meta-analysis.
There are less comparisons among once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs),which is not conducive to refined clinical treatment. We searched in Pubmed, Embase, and Cochrane Central Register of Controlled Trials from database creation date to June 1, 2024. The primary glycemic…
PMID42618994DOI10.1016/j.diabres.2025.112954연구 유형체계적 문헌고찰, 리뷰학술지Diabetes research and clinical practice
https://pubmed.ncbi.nlm.nih.gov/42618994/문헌 79tofacitinib근거 검토우선순위 낮음
Comparison of efficacy and safety of oral corticosteroid mini pulse versus oral tofacitinib in stabilization of active vitiligo: A 24-week randomized controlled assessor-blinded clinical trial with evaluation of serum IL-6 as a surrogate marker.
PubMed에 초록이 제공되지 않았습니다.
PMID42628800DOI10.1016/j.jaad.2026.08.061연구 유형기타학술지Journal of the American Academy of Dermatology
https://pubmed.ncbi.nlm.nih.gov/42628800/문헌 80tofacitinibICSR 검토우선순위 중간
Tocilizumab-induced inflammatory flare in Takayasu arteritis: a case report with exploratory mechanistic findings of Fcγ receptor involvement.
To report a refractory Takayasu arteritis (TAK) patient who developed a severe inflammatory flare after tocilizumab (TCZ) therapy and explore the underlying mechanism. A 21-year-old female with active TAK received TCZ after insufficient response to prednisone. TCZ was temporarily withheld then re-a…
PMID42614358DOI10.3389/fimmu.2026.1898851연구 유형증례보고학술지Frontiers in immunology
https://pubmed.ncbi.nlm.nih.gov/42614358/문헌 81tofacitinibICSR 검토우선순위 중간
Tofacitinib demonstrates favorable efficacy but an increased risk of herpes zoster in elderly patients with rheumatoid arthritis: a retrospective cohort analysis.
To evaluate the efficacy of tofacitinib in elderly patients with rheumatoid arthritis (RA) and analyze herpes zoster risk factors. A retrospective analysis included elderly RA patients from January 2022 to June 2024. Patients were assigned to a tofacitinib group (n=62, tofacitinib + methotrexate) o…
PMID42631130DOI10.62347/BSFE7199연구 유형기타학술지American journal of translational research
https://pubmed.ncbi.nlm.nih.gov/42631130/문헌 82valproate근거 검토우선순위 낮음
Development of Phenoxyacetic Acid Hybrids With COX-2 Inhibitory Activity as Potential Anti-Neuroinflammatory Agents.
This research employs a molecular hybridization strategy to repurpose the pyrazoline scaffold 6a, 6c, 7a-c, 11a, and 12b, transforming it into a high-efficiency conjugate designed to tackle the multifaceted pathology of neuroinflammation and epilepsy. By integrating a selective phenoxyacetic acid m…
PMID42606530DOI10.1002/ddr.70363연구 유형기타학술지Drug development research
https://pubmed.ncbi.nlm.nih.gov/42606530/문헌 83valproate근거 검토우선순위 낮음
Assessment of the impact of valproic acid co-administration on clozapine plasma concentrations in Tunisian patients.
Reports on drug-drug interactions between Valproic Acid (VPA) and Clozapine (CLZ) are very inconsistent. Previous reports demonstrate that VPA may exhibit either inhibitory or inductive effects or have no effect on CLZ pharmacokinetics. The aim of this study was to investigate the impact of VPA on…
PMID42634932DOI10.1515/dmpt-2026-0018연구 유형기타학술지Drug metabolism and personalized therapy
https://pubmed.ncbi.nlm.nih.gov/42634932/문헌 84valproateICSR 검토우선순위 중간
Cell-based Therapies and Drug Repurposing in Stroke.
Ischemic stroke is a leading cause of death and disability worldwide, and contributes substantially to the global burden of disease. Although reperfusion therapies such as intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) and mechanical thrombectomy have transformed acu…
PMID42633921DOI10.1272/jnms.JNMS.2026_93-510연구 유형기타학술지Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
https://pubmed.ncbi.nlm.nih.gov/42633921/문헌 85valproate근거 검토우선순위 낮음
A comparative study of the impact of maternal immune activation and valproic acid on autism-like behavior in rats.
The present study aimed to evaluate the behavioral consequences of maternal immune activation (MIA) induced by lipopolysaccharide (LPS), in comparison to valproic acid (VPA), a widely used and reliable inducer of autism-like features in rats when administered during prenatal development. At the beh…
PMID42633072DOI10.1515/tnsci-2025-0402연구 유형기타학술지Translational neuroscience
https://pubmed.ncbi.nlm.nih.gov/42633072/문헌 86valproate근거 검토우선순위 낮음
Attitudes toward sodium valproate use, withdrawal, and counseling in people of reproductive potential: A scoping review.
Regulatory restrictions and evolving clinical guidelines have aimed to reduce sodium valproate use in people of reproductive potential over the past decade due to its teratogenic risk. While clinical evidence and policy responses are well established, stakeholder perspectives remain less explored.…
PMID42627711DOI10.1002/epi4.70342연구 유형리뷰학술지Epilepsia open
https://pubmed.ncbi.nlm.nih.gov/42627711/문헌 87valproate근거 검토우선순위 낮음
Accountability for AI harms? Lessons from valproate.
PubMed에 초록이 제공되지 않았습니다.
PMID42625357DOI10.1177/01410768261479496연구 유형기타학술지Journal of the Royal Society of Medicine
https://pubmed.ncbi.nlm.nih.gov/42625357/문헌 88valproate근거 검토우선순위 낮음
Intergenerational Consequences of Valproic Acid Exposure: Dose- and Sex-Specific Effects in Drosophila melanogaster.
Valproic acid (VPA) is a widely used anticonvulsant and mood stabilizer, that is notable for its role as histone deacetylase (HDAC) inhibitor and its potential impact on epigenetic modulation. However, its intergenerational impacts are not fully understood. In this study, we investigated the dose-…
PMID42624452DOI10.1016/j.ejphar.2026.179271연구 유형기타학술지European journal of pharmacology
https://pubmed.ncbi.nlm.nih.gov/42624452/문헌 89valproate근거 검토우선순위 낮음
Bioactivity-guided isolation of anticonvulsant and anxiolytic constituents from Stachys and Teucrium species.
Species of the genera Stachys L. and Teucrium L. (Lamiaceae) have been traditionally used in folk medicine for the management of neurological disorders, including epilepsy and anxiety. However, experimental evidence supporting these traditional claims remains limited for several taxa. The present s…
PMID42624443DOI10.1016/j.jep.2026.122299연구 유형기타학술지Journal of ethnopharmacology
https://pubmed.ncbi.nlm.nih.gov/42624443/문헌 90valproate근거 검토우선순위 낮음
Integrated network pharmacology and lipidomics provide insights into potential mechanisms underlying the effects of cannabidiol in a rat model of autism.
Cannabidiol (CBD) has shown potential benefits in managing symptoms associated with autism spectrum disorder (ASD), although its underlying mechanisms of action remain unclear. This study investigated whether CBD improves ASD-like behavior in association with changes in lipid metabolic disturbances…
PMID42632396DOI10.1016/j.psychres.2026.117405연구 유형기타학술지Psychiatry research
https://pubmed.ncbi.nlm.nih.gov/42632396/문헌 91valproate근거 검토우선순위 낮음
Male use of valproate - regulation before evidence?
PubMed에 초록이 제공되지 않았습니다.
PMID42622404DOI10.4045/tidsskr.26.0246연구 유형기타학술지Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
https://pubmed.ncbi.nlm.nih.gov/42622404/문헌 92valproate근거 검토우선순위 낮음
Black mulberry fruit extract attenuates valproic acid-induced toxicity by enhancing antioxidant defenses in FaO cells.
Valproic acid (VPA) is widely used to treat neurological and psychiatric disorders but may cause hepatotoxicity partly through oxidative stress and impaired cellular metabolism. This study investigated whether black mulberry (Morus nigra L.) fruit extract attenuates VPA-induced injury in rat FaO he…
PMID42621753DOI10.17305/bb.2026.14532연구 유형기타학술지Biomolecules & biomedicine
https://pubmed.ncbi.nlm.nih.gov/42621753/문헌 93valproate근거 검토우선순위 낮음
Identification of the M1-like macrophage-associated diagnostic and therapeutic frameworks targeting carotid atherosclerosis patients: Integrative bioinformatic and multi-omic studies.
M1‑like macrophage dysregulation is a central driver of inflammation and plaque formation in atherosclerosis (AS). However, specific diagnostic and therapeutic targets for carotid atherosclerotic plaque remain incomplete. This study aims to identify M1‑like macrophage‑associated diagnostic biomarke…
PMID42628487DOI10.1016/j.compbiolchem.2026.109259연구 유형기타학술지Computational biology and chemistry
https://pubmed.ncbi.nlm.nih.gov/42628487/문헌 94valproateICSR 검토우선순위 중간
Unmasked Behavioral Disturbance Following Traumatic Brain Injury in an Adult With Previously Undiagnosed Sotos Syndrome.
Sotos syndrome is a rare autosomal dominant disorder characterized by childhood overgrowth, including tall stature and macrocephaly, distinctive facial appearance, and neuropsychiatric manifestations. These features include intellectual disability and a broad spectrum of behavioral disturbances. Tr…
PMID42621581DOI10.7759/cureus.113036연구 유형증례보고학술지Cureus
https://pubmed.ncbi.nlm.nih.gov/42621581/문헌 95valproateICSR 검토우선순위 중간
When Surgical Intervention Becomes a Risk: Severe Drug-Induced Gingival Overgrowth and Clinical Decision-Making in Alpers-Huttenlocher Syndrome.
Alpers-Huttenlocher syndrome (AHS) is an ultra-rare, autosomal recessive mitochondrial encephalopathy caused by pathogenic POLG variants, characterized by refractory epilepsy, hepatic dysfunction, and progressive neurodegeneration. Drug-induced gingival overgrowth (DIGO) is a recognized complicatio…
PMID42635616DOI10.1111/scd.70241연구 유형증례보고학술지Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
https://pubmed.ncbi.nlm.nih.gov/42635616/문헌 96valproateICSR 검토우선순위 중간
Cost-Effectiveness and Cost-Utility Analysis of Cinnarizine Compared to Valproate in Pediatric Migraine: An Iranian Perspective.
Childhood migraine is a prevalent neurovascular disease in children with a considerable reduction in quality of life and high social cost. Anticonvulsants, such as Valproate and calcium channel blockers, including Cinnarizine are used frequently as preventive medications. This research evaluates th…
PMID42626205DOI10.22037/ijcn.v20i3.50463연구 유형기타학술지Iranian journal of child neurology
https://pubmed.ncbi.nlm.nih.gov/42626205/