valproate우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42621753
Black mulberry fruit extract attenuates valproic acid-induced toxicity by enhancing antioxidant defenses in FaO cells.
Black mulberry fruit extract attenuates valproic acid-induced toxicity by enhancing antioxidant defenses in FaO cells.
- 저자
- Iza Oblak, Nebojša Pavlović, Saša Vukmirović, Dušan Šuput, Nebojša Stilinović, Irina Milisav
- 저널
- Biomolecules & biomedicine
- 공개일
- 2026 Aug 18
- 연구 유형
- 기타
- DOI
- 10.17305/bb.2026.14532
문헌 요약
Valproic acid (VPA) is widely used to treat neurological and psychiatric disorders but may cause hepatotoxicity partly through oxidative stress and impaired cellular metabolism. This study investigated whether black mulberry (Morus nigra L.) fruit extract attenuates VPA-induced injury in rat FaO hepatoma cells. Cells were exposed to VPA acutely (500 μg/mL…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.