valproate우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42606530
Development of Phenoxyacetic Acid Hybrids With COX-2 Inhibitory Activity as Potential Anti-Neuroinflammatory Agents.
Development of Phenoxyacetic Acid Hybrids With COX-2 Inhibitory Activity as Potential Anti-Neuroinflammatory Agents.
- 저자
- Mohammad H Alqarni, Mahmoud Abdelrahman Alkabbani, Aya Mohamed Ahmed Ibrahim, Ahmed I Foudah, Tariq M Aljarba, Aftab Alam
- 저널
- Drug development research
- 공개일
- 2026 Sep
- 연구 유형
- 기타
- DOI
- 10.1002/ddr.70363
문헌 요약
This research employs a molecular hybridization strategy to repurpose the pyrazoline scaffold 6a, 6c, 7a-c, 11a, and 12b, transforming it into a high-efficiency conjugate designed to tackle the multifaceted pathology of neuroinflammation and epilepsy. By integrating a selective phenoxyacetic acid moiety. Our findings identified compound 7c as a potential…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.