valproate우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42633072
A comparative study of the impact of maternal immune activation and valproic acid on autism-like behavior in rats.
A comparative study of the impact of maternal immune activation and valproic acid on autism-like behavior in rats.
- 저자
- Maha K Alaskar, Mona Alonazi, Abir Ben Bacha, Abdulaziz M Alamri, Sameera Abuaish, Hisham S Aloudah
- 저널
- Translational neuroscience
- 공개일
- 2026 Jan
- 연구 유형
- 기타
- DOI
- 10.1515/tnsci-2025-0402
문헌 요약
The present study aimed to evaluate the behavioral consequences of maternal immune activation (MIA) induced by lipopolysaccharide (LPS), in comparison to valproic acid (VPA), a widely used and reliable inducer of autism-like features in rats when administered during prenatal development. At the behavioral level, we further assessed the potential ameliorat…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.