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LITERATURE DETAIL · PMID 42635616
When Surgical Intervention Becomes a Risk: Severe Drug-Induced Gingival Overgrowth and Clinical Decision-Making in Alpers-Huttenlocher Syndrome.
When Surgical Intervention Becomes a Risk: Severe Drug-Induced Gingival Overgrowth and Clinical Decision-Making in Alpers-Huttenlocher Syndrome.
- 저자
- Marcus Vinícius Bueno, Renata Zoraida Rizental Delgado, Karem Ortega, Juliana Bertoldi Franco
- 저널
- Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
- 공개일
- 2026 Jul-Aug
- 연구 유형
- 증례보고
- DOI
- 10.1111/scd.70241
문헌 요약
Alpers-Huttenlocher syndrome (AHS) is an ultra-rare, autosomal recessive mitochondrial encephalopathy caused by pathogenic POLG variants, characterized by refractory epilepsy, hepatic dysfunction, and progressive neurodegeneration. Drug-induced gingival overgrowth (DIGO) is a recognized complication of anticonvulsant and immunosuppressive therapy, particu…
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