문헌 01apixabanICSR 검토우선순위 중간
Antithrombotic therapy to minimize total events after ACS or PCI in atrial fibrillation: insights from AUGUSTUS.
Antithrombotic therapy for patients with atrial fibrillation (AF) after acute coronary syndrome (ACS) or percutaneous coronary intervention (PCI) requires balancing prevention of stroke and coronary events against bleeding. Recent recurrent-event and patient-centered analyses of AUGUSTUS make this…
PMID42614044DOI10.1097/HCO.0000000000001336연구 유형기타학술지Current opinion in cardiology
https://pubmed.ncbi.nlm.nih.gov/42614044/문헌 02rivaroxabanICSR 검토우선순위 중간
Prescribing patterns of apixaban and rivaroxaban for extended-phase anticoagulant therapy.
Reduced-dose apixaban or rivaroxaban has been suggested for extended-phase anticoagulant therapy for prevention of venous thromboembolism (VTE). The uptake of this suggestion in clinical practice is unclear. The purpose of this study was to describe the prescribing patterns of apixaban and rivaroxa…
PMID41635227DOI10.1093/ajhp/zxag026연구 유형기타학술지American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
https://pubmed.ncbi.nlm.nih.gov/41635227/문헌 03edoxaban근거 검토우선순위 낮음
Heparin-calibrated anti-factor Xa activity as a surrogate marker for direct oral anticoagulant levels in acute stroke care: a large observational single-center study.
Direct oral anticoagulants (DOAC) complicate therapeutic decision-making, as rapid assessment of anticoagulant activity is critical in emergency patients, particularly in acute ischemic stroke (AIS). The administration of systemic thrombolysis (IVT) in anti-coagulated patients requires careful risk…
PMID42613645DOI10.1186/s42466-026-00524-1연구 유형기타학술지Neurological research and practice
https://pubmed.ncbi.nlm.nih.gov/42613645/문헌 04apixabanICSR 검토우선순위 중간
Apixaban Lead-In Versus Lead-In Omission in Hospitalized Adults with Acute Venous Thromboembolism: A Retrospective Safety Analysis.
Apixaban for acute venous thromboembolism (VTE) is dosed with an intensified 7-day lead-in to decrease recurrence. The optimal initiation dosing in hospitalized patients remains unknown. This study compares the safety and efficacy of apixaban maintenance versus lead-in dose initiation in hospitaliz…
PMID42614334DOI10.1177/00185787261476068연구 유형기타학술지Hospital pharmacy
https://pubmed.ncbi.nlm.nih.gov/42614334/문헌 05apixabanICSR 검토우선순위 중간
Vitamin K Antagonist-Induced Calciphylaxis in a Dialysis Patient With Antiphospholipid Syndrome: A Multidisciplinary Case Report.
Calciphylaxis, or calcific uremic arteriolopathy (CUA), is a rare, life-threatening syndrome characterized by microvascular calcification and cutaneous necrosis, predominantly affecting patients with end-stage renal disease (ESRD) on maintenance dialysis, particularly those exposed to vitamin K ant…
PMID42609599DOI10.1155/carm/8244011연구 유형기타학술지Case reports in medicine
https://pubmed.ncbi.nlm.nih.gov/42609599/문헌 06rivaroxabanICSR 검토우선순위 중간
Emergent Reversal of Intracranial Hemorrhage Using 4-Factor Prothrombin Complex Concentrate in a Pediatric Patient.
Direct oral anticoagulant (DOACs) use for pediatric venous thromboembolism has increased, yet data on reversal strategies using 4-factor prothrombin complex concentrate (4F-PCC) remains limited. We report the first case of intracranial hemorrhage (ICH) in a patient receiving rivaroxaban who underwe…
PMID42616581DOI10.1097/MPH.0000000000003261연구 유형기타학술지Journal of pediatric hematology/oncology
https://pubmed.ncbi.nlm.nih.gov/42616581/문헌 07dabigatranICSR 검토우선순위 중간
Unmasking the Hidden Risk: Urticaria and Angioedema with Direct Oral Anticoagulants.
Direct oral anticoagulants (DOACs), such as rivaroxaban and dabigatran, are widely used for thromboembolic conditions. While bleeding is the most well-recognized adverse effect, rare cutaneous hypersensitivity reactions, such as urticaria and angioedema, are increasingly reported. We describe a cas…
PMID42617032DOI10.4103/idoj.idoj_1280_25연구 유형기타학술지Indian dermatology online journal
https://pubmed.ncbi.nlm.nih.gov/42617032/문헌 08warfarinICSR 검토우선순위 중간
Direct oral anticoagulants in elderly patients with atrial fibrillation: a decade-long nationwide retrospective cohort study.
To examine oral anticoagulant (OAC) prescription patterns and clinical outcomes, among elderly patients with atrial fibrillation (AF) during the era of widespread direct oral anticoagulant (DOAC) use. A retrospective cohort study. This study used nationwide electronic health records from multiple c…
PMID42613109DOI10.1136/bmjopen-2026-121683연구 유형기타학술지BMJ open
https://pubmed.ncbi.nlm.nih.gov/42613109/문헌 09semaglutide근거 검토우선순위 낮음
Hunger pain and its reduction; qualitative insight from people with schizophrenia on semaglutide.
It is often reported that people with schizophrenia experience weight gain and disordered eating, partly due to antipsychotics. As part of the RCT "Home-based Intervention with Semaglutide Treatment of Neuroleptic-Related Prediabetes, HISTORI", the present study investigates experiences of hunger a…
PMID42610532DOI10.1080/17482631.2026.2717809연구 유형기타학술지International journal of qualitative studies on health and well-being
https://pubmed.ncbi.nlm.nih.gov/42610532/문헌 10tirzepatideICSR 검토우선순위 중간
Major Adverse Liver Outcomes With Tirzepatide and Injectable Semaglutide in Adults With Overweight or Obesity and Type 2 Diabetes.
This study aimed to compare the effectiveness of tirzepatide versus injectable semaglutide in preventing major adverse liver outcomes (MALO) among adults with overweight or obesity and type 2 diabetes. This retrospective target trial emulation utilized the TriNetX global network to analyze new user…
PMID42618523DOI10.1002/oby.70277연구 유형기타학술지Obesity (Silver Spring, Md.)
https://pubmed.ncbi.nlm.nih.gov/42618523/문헌 11semaglutide근거 검토우선순위 낮음
Experiences of GPs with incretin mimetics: a qualitative study in Germany.
Incretin mimetics are increasingly used to manage diabetes and to support weight loss in people with obesity. However, their application by GPs in primary care settings remains underexplored. This study aimed to investigate GPs' healthcare experiences in relation to incretin mimetics, such as semag…
PMID41238383DOI10.3399/BJGPO.2025.0135연구 유형기타학술지BJGP open
https://pubmed.ncbi.nlm.nih.gov/41238383/문헌 12semaglutideICSR 검토우선순위 중간
Hypoglycaemic coma induced by a falsified semaglutide product: a case report.
Semaglutide (Ozempic, Rybelsus, Wegovy) is a GLP-1 receptor agonist used for the treatment of type 2 diabetes and, more recently, weight management. Due to its efficacy in weight loss, semaglutide has gained worldwide popularity, particularly the branded version Ozempic, resulting in off-label use…
PMID41125326DOI10.1136/ejhpharm-2025-004656연구 유형기타학술지European journal of hospital pharmacy : science and practice
https://pubmed.ncbi.nlm.nih.gov/41125326/문헌 13tirzepatide근거 검토우선순위 낮음
Prospective changes in sleep quality and depressive symptom burden following initiation of GLP-1-based therapies in patients with obesity: a real-world study.
This study aimed to evaluate short-term changes in depressive symptom burden and sleep quality and factors associated with clinical response in patients with obesity initiating GLP-1-based therapies. In this prospective observational study, patients with obesity initiating semaglutide or tirzepatid…
PMID42611111DOI10.1007/s40618-026-03024-w연구 유형기타학술지Journal of endocrinological investigation
https://pubmed.ncbi.nlm.nih.gov/42611111/문헌 14semaglutideICSR 검토우선순위 중간
Effect of Semaglutide on the Inflammatory Biomarker High-Sensitivity CRP in Patients With Established Cardiovascular Disease and Overweight or Obesity in SELECT: A Prespecified Secondary Analysis.
In SELECT (Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity), among 17 604 patients with known atherosclerotic cardiovascular disease and overweight or obesity, but not diabetes, randomization to the glucagon-like peptide-1 receptor antagonist semaglutide signi…
PMID42610271DOI10.1161/CIRCULATIONAHA.125.074482연구 유형기타학술지Circulation
https://pubmed.ncbi.nlm.nih.gov/42610271/문헌 15semaglutide근거 검토우선순위 낮음
Trends in Usage and Payments for Glucagon-Like Peptide-1 Receptor Agonists in the United States, 2017 to 2022: A Nationally Representative Repeated Cross-Sectional Study.
PubMed에 초록이 제공되지 않았습니다.
PMID42464889DOI10.1161/JAHA.125.046302연구 유형기타학술지Journal of the American Heart Association
https://pubmed.ncbi.nlm.nih.gov/42464889/문헌 16semaglutide근거 검토우선순위 낮음
Influence of GLP-1 Receptor Agonists on Surgical and Nonsurgical Treatment of Ankle Osteoarthritis.
BackgroundGlucagon-like peptide-1 (GLP-1) receptor agonists are widely used for the treatment of obesity and type 2 diabetes mellitus (T2DM), with established metabolic benefits. However, their influence on musculoskeletal outcomes, particularly in patients with ankle osteoarthritis (OA), remains u…
PMID42609010DOI10.1177/19386400261471652연구 유형기타학술지Foot & ankle specialist
https://pubmed.ncbi.nlm.nih.gov/42609010/문헌 17semaglutide근거 검토우선순위 낮음
Letter: Non-Invasive Tests After Semaglutide in MASH as Disease-Activity Readouts Rather Than Response Biomarkers. Authors' Reply.
PubMed에 초록이 제공되지 않았습니다.
PMID42608958DOI10.1111/apt.70897연구 유형기타학술지Alimentary pharmacology & therapeutics
https://pubmed.ncbi.nlm.nih.gov/42608958/문헌 18semaglutide근거 검토우선순위 낮음
Review Article: Fibrosis Reversal in Metabolic Dysfunction-Associated Steatohepatitis-The Promise of Emerging Therapeutics.
Metabolic dysfunction-associated steatohepatitis (MASH) is a leading indication for liver transplantation, and fibrosis stage most strongly predicts clinical outcomes. Pharmacologic treatment is now available with resmetirom and semaglutide holding conditional approval. To describe the therapeutic…
PMID42608656DOI10.1111/apt.70921연구 유형기타학술지Alimentary pharmacology & therapeutics
https://pubmed.ncbi.nlm.nih.gov/42608656/문헌 19semaglutideICSR 검토우선순위 중간
Maximizing weight loss with cagrisema: a systematic review and GRADE-assessed meta-analysis of randomized controlled trials.
To evaluate the efficacy and safety of CagriSema, a fixed-dose combination of cagrilintide, a long-acting amylin analogue, and semaglutide, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, compared with placebo, cagrilintide, or semaglutide monotherapy in overweight or obese individuals. A syste…
PMID42608559DOI10.1007/s00210-026-05809-5연구 유형기타학술지Naunyn-Schmiedeberg's archives of pharmacology
https://pubmed.ncbi.nlm.nih.gov/42608559/문헌 20semaglutide근거 검토우선순위 낮음
Gastric content and aspiration risk after semaglutide cessation.
PubMed에 초록이 제공되지 않았습니다.
PMID42608018DOI10.1111/anae.70319연구 유형기타학술지Anaesthesia
https://pubmed.ncbi.nlm.nih.gov/42608018/문헌 21semaglutide근거 검토우선순위 낮음
Efficacy of Luseogliflozin Added to Semaglutide in Patients With Metabolic Dysfunction-Associated Steatohepatitis and Type 2 Diabetes Mellitus: A Randomised, Open-Label Trial.
Type 2 diabetes drives the progression of metabolic dysfunction-associated steatohepatitis (MASH). We evaluated whether antidiabetic therapy, specifically adding sodium-glucose cotransporter 2 (SGLT2) inhibitor to a glucagon-like peptide-1 receptor agonist (GLP-1RA), improves liver histology in adu…
PMID42605535DOI10.1111/dom.71233연구 유형기타학술지Diabetes, obesity & metabolism
https://pubmed.ncbi.nlm.nih.gov/42605535/문헌 22semaglutideICSR 검토우선순위 중간
Semaglutide for primary prevention of major adverse cardiac and cerebrovascular events in patients with type 2 diabetes and comorbid rheumatoid arthritis: a target-trial emulation.
Rheumatoid arthritis (RA)-related physical limitations often hinder sustained physical activity and weight management, thereby amplifying cardiovascular risk through adverse metabolic profiles and chronic inflammation. We aimed to assess the effectiveness of semaglutide on the risk of incident majo…
PMID42334436DOI10.1093/ehjcvp/pvag044연구 유형기타학술지European heart journal. Cardiovascular pharmacotherapy
https://pubmed.ncbi.nlm.nih.gov/42334436/문헌 23tirzepatideICSR 검토우선순위 중간
Glucagon-Like Peptide-1 Receptor Agonists for Obstructive Sleep Apnea With and Without Continuous Positive Airway Pressure.
To evaluate glucagon-like peptide 1 receptor agonists for obstructive sleep apnea compared with controls. CINAHL, Cochrane Library, PubMed, and Scopus. A PRISMA-compliant search was conducted from database inception through October 2025. Randomized controlled trials evaluating glucagon-like peptide…
PMID42611692DOI10.1002/ohn.70407연구 유형기타학술지Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
https://pubmed.ncbi.nlm.nih.gov/42611692/문헌 24tofacitinib근거 검토우선순위 낮음
Real-world effectiveness of tofacitinib in monotherapy or in combination with csDMARDs in patients with rheumatoid arthritis: A collaboration between Dutch registries (TOFADUDAP study).
To compare real-world effectiveness of tofacitinib monotherapy to adalimumab monotherapy, and tofacitinib and adalimumab in combination with csDMARDs in Rheumatoid Arthritis (RA) subgroups. Retrospective routine care data was used from six Dutch cohorts for RA patients who initiated tofacitinib or…
PMID42616227DOI10.1007/s10067-026-08362-x연구 유형기타학술지Clinical rheumatology
https://pubmed.ncbi.nlm.nih.gov/42616227/문헌 25valproateICSR 검토우선순위 중간
Paternal Valproate Exposure and Offspring Neurodevelopmental Outcomes.
Evidence remains inconclusive on whether paternal valproate exposure during spermatogenesis is associated with adverse offspring outcomes, with findings lacking beyond Nordic countries. This study aimed to assess the risks of neurodevelopmental disorders (NDDs) and congenital malformations in offsp…
PMID42617146DOI10.1212/WNL.0000000000218375연구 유형기타학술지Neurology
https://pubmed.ncbi.nlm.nih.gov/42617146/문헌 26valproate근거 검토우선순위 낮음
Paternal Valproate and Offspring Neurodevelopment: A Non-Nordic Perspective on an Unsettled Question.
PubMed에 초록이 제공되지 않았습니다.
PMID42617145DOI10.1212/WNL.0000000000218516연구 유형기타학술지Neurology
https://pubmed.ncbi.nlm.nih.gov/42617145/문헌 27valproate근거 검토우선순위 낮음
C-C motif chemokine 3 interferes with oligodendrocyte maturation in the brain.
White matter alteration caused by abnormal myelination is a major contribution to the pathophysiology of autism spectrum disorder (ASD). We previously reported that mice prenatally exposed to valproic acid (VPA) showed increased expression of C-C motif chemokine ligand 3 (CCL3) in the developing hi…
PMID42235329DOI10.1016/j.bbrc.2026.154081연구 유형기타학술지Biochemical and biophysical research communications
https://pubmed.ncbi.nlm.nih.gov/42235329/문헌 28valproate근거 검토우선순위 낮음
Behavioral pharmacology of isolated cannabidiol in animal models of autism spectrum disorder: a systematic review.
Autism spectrum disorder (ASD) is characterized by differences and challenges in social communication and interaction, restricted and repetitive behaviors, and variable cognitive alterations. Cannabidiol (CBD), a non-psychoactive phytocannabinoid with a complex pharmacological profile, has been inv…
PMID42616101DOI10.1007/s00213-026-07149-x연구 유형기타학술지Psychopharmacology
https://pubmed.ncbi.nlm.nih.gov/42616101/문헌 29valproate근거 검토우선순위 낮음
A global comparison of clinical guidelines for the diagnosis and management of migraine: similarities, differences, and gaps.
To compare international clinical guidelines for migraine diagnosis and management, identifying consensus, differences, and gaps. Assessed guideline repositories and society websites from 2012 to 2025 for recommendations from American, British, Italian, Japanese, French, and International Headache…
PMID42615620DOI10.1097/WCO.0000000000001510연구 유형기타학술지Current opinion in neurology
https://pubmed.ncbi.nlm.nih.gov/42615620/문헌 30valproate근거 검토우선순위 낮음
Effects of artichoke extracts and probiotic on maternal immunological activation, valproic acid-induced oxidative stress, and gut leakiness in a rat model of autism.
Maternal health during pregnancy is a leading factor influencing offspring risk. This study investigated whether postnatal dietary supplementation could reduce oxidative stress and gut leakiness in a rat model of autism spectrum disorder (ASD). Male rat pups were prenatally exposed to valproic acid…
PMID42609554DOI10.1515/biol-2025-1355연구 유형기타학술지Open life sciences
https://pubmed.ncbi.nlm.nih.gov/42609554/문헌 31valproateICSR 검토우선순위 중간
Clinical and neurophysiology study of 17 children with epileptic negative myoclonus.
Epileptic negative myoclonus (ENM) is a clinically underrecognized seizure type, and systematic data on its clinical manifestations and optimal management strategies in pediatric populations remain scarce. This case series aimed to describe the clinical manifestations, neurophysiological patterns,…
PMID42608724DOI10.1186/s42494-026-00273-3연구 유형기타학술지Acta epileptologica
https://pubmed.ncbi.nlm.nih.gov/42608724/문헌 32valproate근거 검토우선순위 낮음
Morin, a bioflavonoid from a traditional medicinal plant, attenuates inflammasome-associated neuroinflammation in drug-resistant epilepsy.
Morin, a bioflavonoid abundant in Morus alba (Moraceae) and traditionally used in Ayurveda and Chinese medicine for the treatment of convulsions and inflammation, modulates neuroinflammatory pathways relevant to epilepsy. This study investigated the effects of morin on inflammasome-associated neuro…
PMID42607854DOI10.1016/j.ejphar.2026.179241연구 유형기타학술지European journal of pharmacology
https://pubmed.ncbi.nlm.nih.gov/42607854/문헌 33valproateICSR 검토우선순위 중간
Safety of Antiseizure Medications During Direct Oral Anticoagulant Therapy in Epilepsy.
Concomitant use of antiseizure medications (ASMs) and direct oral anticoagulants (DOACs) is common in epilepsy, but comparative safety data remain limited. To compare risks of thromboembolic events, major bleeding, and all-cause mortality across commonly used ASMs in adults with epilepsy receiving…
PMID42606848DOI10.1001/jamaneurol.2026.2712연구 유형기타학술지JAMA neurology
https://pubmed.ncbi.nlm.nih.gov/42606848/