valproate우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42609554
Effects of artichoke extracts and probiotic on maternal immunological activation, valproic acid-induced oxidative stress, and gut leakiness in a rat model of autism.
Effects of artichoke extracts and probiotic on maternal immunological activation, valproic acid-induced oxidative stress, and gut leakiness in a rat model of autism.
- 저자
- Maha K Alaskar, Mona Alonazi, Abir Ben Bacha, Abdulaziz Mohammad Alamri, Musarat Amina, Nawal M Al Musayeib
- 저널
- Open life sciences
- 공개일
- 2026 Jan
- 연구 유형
- 기타
- DOI
- 10.1515/biol-2025-1355
문헌 요약
Maternal health during pregnancy is a leading factor influencing offspring risk. This study investigated whether postnatal dietary supplementation could reduce oxidative stress and gut leakiness in a rat model of autism spectrum disorder (ASD). Male rat pups were prenatally exposed to valproic acid (VPA) or lipopolysaccharide (LPS) to induce ASD-like cond…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.