valproate우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42235329
C-C motif chemokine 3 interferes with oligodendrocyte maturation in the brain.
C-C motif chemokine 3 interferes with oligodendrocyte maturation in the brain.
- 저자
- Sakuno Nishimura, Hana Okino, Nami Ishihara, Tatsuto Nakane, Christoph F A Vogel, Kouichi Itoh
- 저널
- Biochemical and biophysical research communications
- 공개일
- 2026 Aug 20
- 연구 유형
- 기타
- DOI
- 10.1016/j.bbrc.2026.154081
문헌 요약
White matter alteration caused by abnormal myelination is a major contribution to the pathophysiology of autism spectrum disorder (ASD). We previously reported that mice prenatally exposed to valproic acid (VPA) showed increased expression of C-C motif chemokine ligand 3 (CCL3) in the developing hippocampus, and that antagonizing C-C chemokine receptor ty…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.