tofacitinib우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42562116
Superior Effectiveness of Upadacitinib Over Tofacitinib and Ustekinumab in Bio-Exposed Ulcerative Colitis: The TRIDENT-UC Study.
Superior Effectiveness of Upadacitinib Over Tofacitinib and Ustekinumab in Bio-Exposed Ulcerative Colitis: The TRIDENT-UC Study.
- 저자
- Joana Camões Neves, Dalila Costa, Margarida Cristiano, Francisco Portela, Ana Rita Fernandes, Samuel Fernandes
- 저널
- Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
- 공개일
- 2026 Aug 06
- 연구 유형
- 기타
- DOI
- 10.1016/j.cgh.2026.07.020
문헌 요약
Despite the progress in advanced therapies (AT) for ulcerative colitis (UC), selecting a second-line treatment after failure remains challenging. Recent guidelines recommend upadacitinib, tofacitinib or ustekinumab as high-efficacy options after prior AT failure. However, real-world comparative data among these three agents are lacking. Retrospective mult…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.