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LITERATURE DETAIL · PMID 42552238

GLP-1 Receptor Agonist Therapy for Obesity Under Japan's Optimal Use Guideline: A Prospective Real-World Study of Lifestyle Pre-Treatment, Time-Limited Treatment Cap, and Post-Cessation Regain.

GLP-1 Receptor Agonist Therapy for Obesity Under Japan's Optimal Use Guideline: A Prospective Real-World Study of Lifestyle Pre-Treatment, Time-Limited Treatment Cap, and Post-Cessation Regain.

저자
Susumu Inamine, Yasunori Uesato
저널
Diabetes, obesity & metabolism
공개일
2026 Aug 04
연구 유형
기타
DOI
10.1111/dom.71190

문헌 요약

Japan's optimal use guideline restricts insurance-reimbursed GLP-1 receptor agonist (GLP-1 RA) therapy for obesity to patients completing a mandatory 6-month lifestyle intervention, caps treatment at 68 weeks (semaglutide 2.4 mg) or 72 weeks (tirzepatide), and mandates subsequent washout. We evaluated the clinical implications of this regulated program in…

PV 검토 포인트

누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.

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