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LITERATURE DETAIL · PMID 42549483

Age-associated B cells contribute to inflammation via antibody-independent mechanisms in Takayasu's arteritis.

Age-associated B cells contribute to inflammation via antibody-independent mechanisms in Takayasu's arteritis.

저자
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao
저널
Arthritis & rheumatology (Hoboken, N.J.)
공개일
2026 Aug 04
연구 유형
기타
DOI
10.1002/art.70284

문헌 요약

Although Takayasu's arteritis (TAK) is not a prototypical autoantibody-mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B-cell activation and its contributions to TAK pathogenesis. Histological analysis of paravascular lymph nodes and affected arteries was conducted to investigate B…

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