valproate우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42517197
Combined effects of melatonin and valproic acid in cerebral ischemia via modulation of oxidative stress and melatonin receptors.
Combined effects of melatonin and valproic acid in cerebral ischemia via modulation of oxidative stress and melatonin receptors.
- 저자
- Parisa Firouzi, Elham Ghasemloo, Meysam Forouzandeh, Mehdi Eskandari, Mahin Ganjkhani, Massomeh Hosseini
- 저널
- Neurological research
- 공개일
- 2026 Jul 28
- 연구 유형
- 기타
- DOI
- 10.1080/01616412.2026.2711004
문헌 요약
Ischemic stroke is a major cause of mortality and disability worldwide, with limited effective neuroprotective treatments. Epigenetic modulation and oxidative stress regulation have emerged as promising therapeutic targets. This study aimed to evaluate the neuroprotective effects of melatonin and valproic acid, alone and in combination, in a rat model of…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.