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LITERATURE DETAIL · PMID 42500898

Association of Genetic Variants With Rivaroxaban Pharmacokinetics and Pharmacodynamics in Older Patients With Atrial Fibrillation: A Prospective Cohort Study.

Association of Genetic Variants With Rivaroxaban Pharmacokinetics and Pharmacodynamics in Older Patients With Atrial Fibrillation: A Prospective Cohort Study.

저자
Guoquan Chen, Haiping Wang, Jiale Chen, Ling Wang, Qiang Zhao, Ganbo Que
저널
Journal of the American Heart Association
공개일
2026 Aug 04
연구 유형
기타
DOI
10.1161/JAHA.126.049831

문헌 요약

Rivaroxaban is frequently used for stroke prevention in atrial fibrillation. Clinicians increasingly encounter complex decision-making regarding oral anticoagulant prescription in older patients with atrial fibrillation. Genetic contributors to variability in rivaroxaban exposure and clinical outcomes remain uncertain. A total of 168 eligible participants…

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