tofacitinib우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42497584
Evaluating the cardiometabolic impact of Janus-kinase inhibition: An experimental analysis of Tofacitinib's therapeutic potential in a rodent model.
Evaluating the cardiometabolic impact of Janus-kinase inhibition: An experimental analysis of Tofacitinib's therapeutic potential in a rodent model.
- 저자
- Vera Tarjányi, Anna Szilágyi, Réka Szekeres, Barbara Takács, Balázs Varga, Dániel Priksz
- 저널
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 공개일
- 2026 Jul 24
- 연구 유형
- 기타
- DOI
- 10.1016/j.biopha.2026.119772
문헌 요약
Rheumatoid arthritis (RA) is the most prevalent non-infectious inflammatory disorder, often associated with comorbidities such as cardiovascular alterations and metabolic syndrome. These comorbidities significantly influence RA activity, flare duration, and treatment outcomes. This study investigated the effects of the Janus-kinase (JAK) inhibitor on card…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.