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LITERATURE DETAIL · PMID 42497137
Research advances in key genes and regulatory mechanisms of posttranslational modifications in Parkinson's disease.
Research advances in key genes and regulatory mechanisms of posttranslational modifications in Parkinson's disease.
- 저자
- Bangzhi Wang, Zhuo Huang, Rong Wang, Chaolin Zhu, Shijiang Ma, Minghong Wang
- 저널
- PloS one
- 공개일
- 2026
- 연구 유형
- 기타
- DOI
- 10.1371/journal.pone.0354097
문헌 요약
The genesis of Parkinson's disease (PD), a common central neurodegenerative disorder, involves dysregulation of protein posttranslational modifications (PTM). The primary objective of this study was to screen key PTM-associated genes (PTMGs) serving as diagnostic indicators and potential therapeutic targets in PD. Peripheral blood transcriptomic data for…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.