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LITERATURE DETAIL · PMID 42492292

Nanoparticle Biofunctionalization of Bioprosthetic Heart Valves to Modulate Mechanisms of Structural Valve Deterioration.

Nanoparticle Biofunctionalization of Bioprosthetic Heart Valves to Modulate Mechanisms of Structural Valve Deterioration.

저자
Angus J Grant, Alex H P Chan, Xueying S Xu, Kieran Lau, Timothy C Mitchell, Juichien Hung
저널
JACC. Basic to translational science
공개일
2026 Jul 23
연구 유형
기타
DOI
10.1016/j.jacbts.2026.101641

문헌 요약

Bioprosthetic heart valves made from glutaraldehyde-fixed animal pericardium are widely used for valve replacement but are prone to early degeneration arising from the interplay of thrombosis, inflammation, and calcification. Current chemical treatments passivate the tissue surface but do not address these biological processes. This study introduces a pla…

PV 검토 포인트

누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.

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