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LITERATURE DETAIL · PMID 42486853

AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models.

AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models.

저자
Ashmita Saigal, Desiree Abdurrachim, Emily Tso, Christopher Hendra, Charlene Zhi Lin Ong, Sonya Kimball
저널
Nature communications
공개일
2026 Jul 22
연구 유형
기타
DOI
10.1038/s41467-026-73370-z

문헌 요약

Optimizing murine models for studying Metabolic Dysfunction-Associated Steatohepatitis (MASH) and fibrosis is crucial for understanding disease mechanisms and evaluating therapies. In this study, we characterized diet-induced male murine models of MASH and liver fibrosis using an AI-digital pathology (DP) pipeline for zone-specific analysis and spatial (c…

PV 검토 포인트

누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.

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