tofacitinib우선순위 중간ICSR 검토기타
LITERATURE DETAIL · PMID 42485112
Effectiveness of tofacitinib as rescue therapy in biological-naive patients with steroid-refractory acute severe ulcerative colitis: a multicentric retrospective analysis.
Effectiveness of tofacitinib as rescue therapy in biological-naive patients with steroid-refractory acute severe ulcerative colitis: a multicentric retrospective analysis.
- 저자
- Suprabhat Giri, Kayal Vizhi, Sumaswi Angadi, Shivaraj Afzalpurkar, Gaurav Khatana, Sunil Kasturi
- 저널
- European journal of gastroenterology & hepatology
- 공개일
- 2026 Jul 20
- 연구 유형
- 기타
- DOI
- 10.1097/MEG.0000000000003254
문헌 요약
Tofacitinib, a Janus kinase inhibitor approved for moderate-to-severe ulcerative colitis, has limited data in acute severe ulcerative colitis (ASUC), particularly in biologic-naive patients. This study evaluated its safety and efficacy as second-line therapy after intravenous steroid failure. The present study retrospectively evaluated patients with biolo…
PV 검토 포인트
개별 증례 가능성과 중대성, 예상성 및 중복 여부를 우선 검토합니다.