semaglutide우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42480913
From FLOW to translational positioning in chronic kidney disease: mechanistic complementarity of SGLT2 inhibitors and GLP-1 receptor agonists.
From FLOW to translational positioning in chronic kidney disease: mechanistic complementarity of SGLT2 inhibitors and GLP-1 receptor agonists.
- 저자
- Xue Tian, Xiaoying Ma, Enxue Song, Xilian Li, Wenlan Fu, Haiwei He
- 저널
- Translational research : the journal of laboratory and clinical medicine
- 공개일
- 2026 Jul 21
- 연구 유형
- 기타
- DOI
- 10.1016/j.trsl.2026.07.008
문헌 요약
Chronic kidney disease is a central node of the cardio-kidney-metabolic continuum and carries substantial residual cardiovascular and kidney risk. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have reproducibly reduced kidney disease progression and heart failure risk in CKD outcomes trials, whereas GLP-1RAs have established cardiovascular benefit ac…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.