VVigilance Weekly공개 리포트 보기
← 이번 주 리포트
dabigatran우선순위 낮음근거 검토기타

LITERATURE DETAIL · PMID 42478503

Screening study of serum thrombosis-related target proteins using a specific dabigatran-functionalized material.

Screening study of serum thrombosis-related target proteins using a specific dabigatran-functionalized material.

저자
Shiqi Dong, Xiaoyan Wang, Hui Niu, Junhong Qian, Lingyi Zhang, Weibing Zhang
저널
Analytical methods : advancing methods and applications
공개일
2026 Jul 21
연구 유형
기타
DOI
10.1039/d6ay01005a

문헌 요약

A drug-related protein profiling strategy was developed based on drug-protein interactions, utilizing a magnetic adsorbent modified with dabigatran (Fe 3 O 4 @SiO 2 @DBG). Dabigatran (DBG), the hydrolytic product of dabigatran etexilate, which is a drug for thromboembolic disease treatment, was covalently immobilized on the surface of the Fe 3 O 4 @SiO 2…

PV 검토 포인트

누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.

PubMed에서 원문 정보 보기