tofacitinib우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42444784
Inhibition of Janus kinase/signal transducer and activator of transcription reduces nociceptive sensitization in a murine model of complex regional pain syndrome.
Inhibition of Janus kinase/signal transducer and activator of transcription reduces nociceptive sensitization in a murine model of complex regional pain syndrome.
- 저자
- Wenwu Li, Dorien Feyaerts, Xiaoyou Shi, Tzuping Wei, Tian-Zhi Guo, Maximilian Sabayev
- 저널
- Pain reports
- 공개일
- 2026 Aug
- 연구 유형
- 기타
- DOI
- 10.1097/PR9.0000000000001475
문헌 요약
Complex regional pain syndrome (CRPS) is a disabling condition relying in part on the production of pain-supporting autoantibodies. The Janus kinase/signal transducer and activator of transcription (JAK-STAT) signaling system regulates the adaptive system of immunity and is targeted to control autoimmune diseases. To evaluate the hypothesis that JAK-STAT…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.