tofacitinib우선순위 낮음근거 검토기타
LITERATURE DETAIL · PMID 42401300
Polymeric mixed micellar nanogel enhances dermal delivery and therapeutic efficacy of tofacitinib citrate.
Polymeric mixed micellar nanogel enhances dermal delivery and therapeutic efficacy of tofacitinib citrate.
- 저자
- Akanksha Mahajan, Gajanand Sharma, Amita Sarwal, Bhupinder Singh, Om Prakash Katare
- 저널
- International journal of pharmaceutics
- 공개일
- 2026 Aug 10
- 연구 유형
- 기타
- DOI
- 10.1016/j.ijpharm.2026.127154
문헌 요약
This study aimed to develop and evaluate a polymeric-surfactant stabilized mixed micellar (MM) gel of tofacitinib citrate (TFC) for localized management of rheumatoid arthritis (RA). TFC-MM gel was formulated via a simple and scalable cold dispersion self-assembly approach using Lipoid S75, Tween 80, and Poloxamer 407, incorporated into a Carbopol hydroge…
PV 검토 포인트
누적 안전성 근거로 분류하고 기존 시그널과의 일관성을 확인합니다.