apixaban우선순위 중간ICSR 검토기타
LITERATURE DETAIL · PMID 41983565
Comparing Hemostatic Efficacy of Four-factor Prothrombin Complex Concentrate with Andexanet Alfa in an Apixaban-treated Polytrauma Male Porcine Model.
Comparing Hemostatic Efficacy of Four-factor Prothrombin Complex Concentrate with Andexanet Alfa in an Apixaban-treated Polytrauma Male Porcine Model.
- 저자
- Oliver Grottke, Till Braunschweig, Lars Heubner, Eva Herzog, Farahnaz Rayatdoost
- 저널
- Anesthesiology
- 공개일
- 2026 Aug 01
- 연구 유형
- 기타
- DOI
- 10.1097/ALN.0000000000006095
문헌 요약
This study directly compared the hemostatic efficacy of two first-line treatments for reversing the effects of direct oral anticoagulants in patients with massive bleeding, andexanet alfa and four-factor prothrombin complex concentrate (4F-PCC), in an apixaban anticoagulated male porcine polytrauma model. Male pigs (N = 32) received 20 mg/day apixaban for…
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