rivaroxaban우선순위 중간ICSR 검토기타
LITERATURE DETAIL · PMID 41776019
Andexanet alfa Reduces Hematoma Expansion Following Controlled Cortical Impact in Mice Pretreated with Rivaroxaban.
Andexanet alfa Reduces Hematoma Expansion Following Controlled Cortical Impact in Mice Pretreated with Rivaroxaban.
- 저자
- Franziska Lieschke, Sarah Gelhard, Michelle Rosenthal-Rueckeis, Christian Grefkes, Ferdinand O Bohmann
- 저널
- Neurocritical care
- 공개일
- 2026 Aug
- 연구 유형
- 기타
- DOI
- 10.1007/s12028-026-02463-w
문헌 요약
With the introduction of andexanet alfa, a specific antidote is now available to address life-threatening bleeding associated with factor Xa inhibitors. In this study, we explore its use in an experimental model of traumatic brain injury (TBI), mimicking a closed head trauma under rivaroxaban-induced anticoagulation. Male C57BL6 mice were fed with rivarox…
PV 검토 포인트
개별 증례 가능성과 중대성, 예상성 및 중복 여부를 우선 검토합니다.